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Figure 6 Klotho Regulation and GH Secretion To date, it has not been clearly established how klotho secretion is regulated, although the fact that the kidneys are the main source of klotho suggests that hormones and factors involved in mineral homeostasis play a role in this regulation

In an analysis conducted at the Menopause Clinic of the University of Athens, 84 healthy women aged 49 to 69 years were studied who had been in menopause for at least one year

"Reporting of surrogate endpoints in randomised controlled trial reports (CONSORT-Surrogate): extension checklist with explanation and elaboration"