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Hum Reprod Update (2019) 25(5):592632

In controls, probiotic supplementation was associated with decreased expression of MS risk allele HLA-DQA1

In light of recent discoveries regarding lactate-mediated Kla in tumor immunology and immunotherapy, this review provides a synthesis of the current understanding of the immunomodulatory effects of Kla and the translational landscape of Kla-targeted therapeutics