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The 4 mg/mL concentration (2.5 mL water) is less common but appears in some compounding pharmacy protocols

This week it is atai Life Sciences and Beckley Psytech reporting the positive results from their Phase 2a open-label study evaluating BPL-003 in Patients with Treatment Resistant Depression

FDA guidance has emphasized that compounded drugs may be appropriate when a patients need cannot be met by an FDA-approved drug or when an FDA-approved drug is not commercially available

The approval was supported by data from the Phase III PRECISION trial, where both the 12.5-mg and 25-mg dose levels of Tryvio significantly reduced sitting systolic blood pressure compared with placebo after four weeks of treatment