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Conclusion: PI3K/Akt signaling potentially enhanced the expression of immune-escape genes and triggered cytokine secretion, leading to alterations in the immune cell infiltration pattern in HCC recurrence

Recently, extracellular matrix derived from mesenchymal stem cells were shown to maintain re-differentiation potential of human chondrocytes ( Conclusion In vitro expanding human chondrocytes to a number that is required by the ACI results in the generation of senescent cells

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