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Future Korean guidelines should acknowledge these real-world limitations while encouraging gradual integration of MRE and IUS

Continuous MT-1 administration beyond 3 weeks causes melanocortin receptor desensitization, where melanocytes downregulate MC1R surface expression in response to sustained agonist binding

Research has shown that creatine is primarily stored in the mitochondria in the form of phosphocreatine

Initial studies in rats caused concerns over GLP-1 RAs causing thyroid cancer, but human studies are less clear on whether it is a concern.[ref] Decreased risk of substance abuse: A large 2026 study using data from the VA showed that GLP-1 RA drugs reduce the risk of developing a substance addiction (drugs, alcohol)