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The dual strategy (targeting and biomimetic) together showed 3 folds increased localized accumulation and selective retention of RNP nanoparticles in vitro studies and the best anti-glioma effect in vivo mice studies (significantly higher survival, i.e., 23 d vs

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Conversely, some studies show that a deficiency in vitamin B12 may cause appetite loss, potentially leading to weight loss if left untreated ( If youre low or deficient in B12, your healthcare provider will likely recommend oral vitamin B12 supplements or injections to increase your blood levels ( summary Low levels of vitamin B12 can cause megaloblastic anemia, which is characterized by shortness of breath, headaches, and fatigue