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Mechanistically, YAP/TAZ induce the expression of SLC7A11 in a TEAD-dependent manner, and sustain the protein stability, nuclear localization, and transcriptional activity of ATF4 which in turn cooperates to induce SLC7A11 expression

Calculation of encapsulation efficiency After a typical encapsulation experiment, PLGA pellets were collected by centrifugation at 12396 g for 20 minutes using a micro centrifuge (Eppendorf 5418, Hamburg, Germany)

Vitamin C deficiency can lead to scurvy, a condition characterized by fatigue, weakness, gum disease and skin abnormalities

Metformin prevents methylglyoxal-induced apoptosis by suppressing oxidative stress in vitro and in vivo