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CDK4/6 inhibition induces epithelial cell cycle arrest and ameliorates acute kidney injury

Of note, transcription of cyclin-dependent kinase inhibitor, p21 ( CDNK1A ) was significantly upregulated in response to GSTO1 knockdown while that of the cell cycle regulatory proteins cyclin D1 ( CCND1 ), cyclin E1 ( CCNE1 ), as well as Myc were found downregulated (GEO accession No

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