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One targets a single process in a single tissue type

46 Progesterone may also be a factor in fibromyalgia pain, with women in a small clinical study reporting greater fibromyalgia pain severity on days when their progesterone levels were lower

& Kang, S

After 30 min pre-incubation, adipocytes were incubated with or without insulin (0.1 ~ 3 nM) for 5 min and the cells were further incubated with isoproterenol (30 or 300 nM) for 30 min