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The most common cause of non-traumatic lower limb amputation in most countries with high earnings, according to recent studies, is distal proximal neuropathy (DPN) (53)

Absolute contraindications are not established due to lack of clinical data

This means they can only be prescribed by a healthcare practitioner in certain circumstances and cannot be advertised

Food colorings, additives, and preserva- tives Potential Symptoms1,15 Monosodium glutamate (MSG) Acne Sulfites Colorings, tartrazine (yellow dye) Arthritis Benzoates Vanillin Asthma Abdominal pain and bloating Diarrhea Fatigue 206 5 Micronutrients as Prevention and Therapy Micronutrients Allergies Nutrient Suggested daily dose Comments Vitamin C 12 g 50100 mg Increases breakdown of histamine produced by the allergic Vitamin B6 24 g as fish-oil capsules response2, thereby reducing symptoms 50100 g May reduce food sensitivities, particularly to additives such Omega-3 fatty as monosodium glutamate acids Reduces inflammation and may decrease symptoms12,13 Vitamin B12 May reduce food sensitivity, particularly to sulfites5 References 9