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DOI: 10.1016/j.anireprosci.2013.03.012 24

After overnight incubation, flow cytometry revealed pSTAT5 activation in CD4, CD8, and CD56 cells only upon MMP7 treatment (Fig

The degradation of glutamine required GLS, glutamate dehydrogenase (GDH) and GOT2 to provide fuel for TCA cycle and lipid biosynthesis

This neuroimmune-tumor connection is also paradoxical as links also exists between chronic inflammation and tumorigenesis, with glioma cells producing pro-inflammatory cytokines, chemokines, and growth factors that create an inflammation-enriched TME (65, 66)