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Much of the research over the last couple of decades has focused on thrombosis and reducing the risk of excessive blood clotting, as this is substantially associated with vascular stiffness, reduced blood flow, and an increased risk of embolism, cardiovascular disease, and heart failure

Over time, skin is exposed to oxidative stress from UV rays, pollution, and even the natural aging process, all of which contribute to the development of age spots, or sun spots, and an uneven complexion