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The proportion of myeloid progenitors (Ba, IMP, Mk, mono and Neu) based on UMAP clustering was reduced, while the proportion of CLP was increased in lineage-negative bone-marrow cells from old Mx1-T3 mice (Fig

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At low concentrations, ROS modulate many cellular processes through redox-dependent signaling including proliferation, differentiation, apoptosis, immune regulation, cellular adaptation [1113] and now it is becoming clear that they also participate in the (negative) regulation of steroidogenesis [7, 8, 10, 23, 55, 56]