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Disagreements were solved by the consensus of a third author (F.F.) The studies had to include individuals with a clinical diagnosis of any type of dementia and severity according to the internationally accepted guidelines or diagnostic criteria

RAW264.7 cells were transfected with Apollo-NADP + sensors targeted to the mitochondria or the cytosol, followed by the treatment of 2-deoxyglucose and diamide

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FIGURE 4 On the other hand, the activity of glutamate dehydrogenase (GDH), a mitochondrial Krebs cycle-associated enzyme, was decreased significantly in the GK rat liver (40%), which recovered after the exercise regimen (Figure 4B)