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In certain cancers, enhanced FAO might exert an inhibitory effect by depleting FA availability, thereby restraining tumor growth

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Combining GPX4 with immunotherapy can further prevent the tumor progression (172, 173)

Chondrocytes are involved in maintaining the integrity of the extracellular matrix and controlling the balance of articular cartilage homeostasis, thereby contributing to the deceleration of OA development (158, 159)