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o In attack treatment : 1 ampoule per day for 15 days to 1 month

doi: 10.1016/s0014-4886(02)00060-2

Pharmacology 58, 281284

Copper Chelation and Delivery At the most fundamental level, GHK functions as a copper chelator and delivery system - the tripeptide binds Cu with exceptionally high affinity (binding constant approximately 10 M, among the highest known for biological copper chelators), forming a square planar coordination complex where the copper ion is coordinated by the nitrogen atoms of the terminal amino group, the two peptide bonds, and the imidazole nitrogen of histidine