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Description

Among these two kinases, mTORC1 plays a key role in maintaining metabolic homeostasis, protein and lipid synthesis, glycolysis, mitochondrial biosynthesis, and lysosomal function by sensing various stimuli, such as amino acids, growth factors, and oxygen, thereby regulating activity of transcription factor and directly modulating translation processes

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Dense binding is observed in the caudate, putamen, cerebral cortex, and amygdala, while they are generally sparse to inexistent in thalamus and hypothalamus

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