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Synbiotics, defined as combinations of probiotics and prebiotics, demonstrate a synergistic effect in modulating the composition and functionality of the intestinal microbiota

Systemic metabolic alterations and their relationship to neuropsychiatric symptomatology PAIS, including long COVID, as well as CFS and IMD, share the characteristic of systemic metabolic disturbances, which may be a sign of underlying multi-organ inflammation and exhaustion [31], and consequently may contribute to neuropsychiatric symptomatology, as many metabolites can cross the bloodbrain barrier (BBB) [30, 58] (e.g., short chain fatty acids (SCFAs) derived from the gut microbiota such as acetate [40], amino acids such as tryptophan [52] and also carnitine/acetylcarnitine can cross the BBB via transporters [59])

Liver Detoxification: Concentrated in the liver, glutathione binds to toxins and aids in their removal from the body, detoxifying the liver and helping manage infections like fatty liver disease

Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease