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Polyamine Synthesis Polyamines constitute a class of low-molecular-weight molecules present in all living cells and crucial to processes involving translation, transcription, cell growth and apoptosis [41]

Plasminogen is everywhere in the blood, but the aim is to have it only activated at the clot, and thereby avoiding unwanted bleeding side effects elsewhere in the body.

Based on these mechanistic associations, these indicators are speculated to serve as potential safety monitoring targets for combined ferroptosis/cuproptosis-targeted therapies in HNSCC

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