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doi: 10.1007/s00253-016-8006-6 Summary Keywords bile acids, gut microbiota, tumor immune microenvironment, cancer immunotherapy, immunometabolism Citation Tong Y and Lou X (2025) Interplay between bile acids, gut microbiota, and the tumor immune microenvironment: mechanistic insights and therapeutic strategies

JAMA, 306 , 26732683

P300 and SIRT1 are the regulators for H3K18la in porcine GCs P300 is currently recognized as the most extensively studied lactyltransferase, reported in humans and mice to catalyze the binding of lactyl-CoA to histone lysine residues in a lactate-dependent manner 23,28 (Fig

Additionally, NETs can aid in mediating liver IRI, promoting tumor progression, and most recently, in mediating early graft rejection in liver transplantation