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The lipid transporter protein Sterol carrier protein 2 (SCP2) transports hydroperoxide species and phospholipid hydroperoxide families to the mitochondria during ferroptosis, promoting lipid peroxidation at the mitochondrial membrane [126, 127]

Furthermore, it was established that Cu 2+ primarily induces cuproptosis in lung cancer KP cells by reducing FDX1 expression levels [173]

rather, it supports them by neutralizing toxins and reducing oxidative damage

The differential microbes in the model group compared to the control group included Actinobacteria, Fusobacteria, Tenericutes, Firmicutes, and Verrucomicrobia (Figure S2e)