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Tocopherol acetate (200 mg/kg, i.p.) increased GSH levels and decreased MDA level in systemic toxicity due to percutaneous administration of SM in animals

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In the human condition Fanconi Anaemia, metabolic ROS were shown to induce DNA damage in hematopoietic stem cells (HSCs) when they start cycling to exit quiescence, which impairs blood production in FancA / mice 51

Efforts to develop non-classical platinum compounds, which form different types of platinum-DNA adducts, have led to the discovery of new platinum-based agents with unique clinical activity