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This is evident especially with HIV-associated lipodystrophy

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In addition to inhibition in the hippocampus, complex II also is inhibited in the posterior cortex (0.1-4.0 mM) and liver (1.0, 2.0 and 4.0 mM)

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The transsulfuration pathway contributes to proper T cell activation and proliferation through the upregulation of cystine and cysteine import ( Figure 1 )

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