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10.1164/rccm.201202-0302OC 141 YuH.ZhangZ.HuangH.WangY.LinB.WuS.et al (2019)

Key risk factors include pregnancy changes, cesarean deliveries, and hormonal therapies

In human vastus lateralis biopsies, MGF mRNA rose 4.5-fold 2.5 hours after a single bout of resistance exercise compared with pre-exercise baseline, while systemic IGF-1 did not change significantly, suggesting a paracrine rather than endocrine role [13]