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Disrupted peripheral neurogenic signaling pathways between the liver and the brain axis, coupled with perturbed central neurotransmission within the brain, in tandem with disease-related or disease-associated factors, such as complications, treatments, and severity, as well as alcohol use, metabolic syndrome, and malignancy, collectively contribute toward clinical fatigue ( 2.3 Diagnosis and management Peripheral fatigue can be quantified through objective assessments of strength and aerobic capacity, while central fatigue is evaluated using self-reports and validated questionnaires that capture the patients perception of physical and mental exertion impacts on their activities and exertion levels

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CrossRef Rapid diagnostics innovations for urinary tract infections using molecular biology, artificial intelligence and antimicrobial resistance surveillance: a comprehensive review Soniya Goyal, Pooja Sharma, Deepak Aggarwal, Sameer Singh Faujdar Molecular Biology Reports.2026;[Epub] CrossRef Editorial for Urogenital Tract Infection (UTI) 2025 Vol