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doi: 10.1016/j.jhep.2022.06.004 123 KothariVSavardCTangJLeeSPSubramanianSWangSet al

It has been reported that Dihydroquercetin (DHQ) inhibited ferritin autophagy and decreased ferrous iron in unstable intracellular iron pools by downregulating microtubule-associated protein 1 A/1B-light chain 3 (LC3) and upregulating ferritin heavy chain 1 (FTH1), as well as nuclear receptor co-activator 4 (NCOA4), in activated HBE cells for silicosis treatment [27]

FOCM and Parkinsons disease PD is the second most common neurodegenerative disorder, impacting about 1% of the population above 60 years [130,131,132]