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However, in that study, the neuronal and glial cells were co-treated with cytotoxic concentrations of H 2 O 2 , and therefore it is unlikely that GGC could produce beneficial effects on GSH in this condition

Studies have shown that hyperglycemia may lead to disruption of ER homeostasis through ER Ca 2+ overload, and metformin may alleviate this disruption

Therefore, the magnetoplexes derived from PEI coated MNPs acquired optimal size and morphology for efficient gene delivery

These interactions are disrupted in schizophrenia, as reflected by dysregulation of synaptic adhesion genes and cholesterol metabolism, both being fundamental for synaptic integrity 305,306