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The cause and effect of errors in the control mechanisms of GCL are slowly being unravelled by researchers and is the subject of several excellent reviews [2-6]

Foley M, Parkinson JT, Mitchell RE, Turner L, Khandaker GM

Despite the limited available evidence on ascorbate level in human brains, the previous study has reported that ascorbate level in the cerebral cortex is declined for nearly 77% from an individual at age 80 and older, compared to that individual at age 50 and younger (Schaus, 1957)

cuproptosis potentially immunosuppressive) complicate combination therapy design and necessitate sophisticated, context-dependent therapeutic sequencing