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Similarities and differences between nigral and enteric dopaminergic neurons unravel distinctive involvement in Parkinson's disease

This study aims to further elucidate the relationship between lactate metabolism and PD and to investigate the potential regulatory effects of irisin on lactate metabolism

[Google Scholar] 166.Jadavji NM, Farr TD, Lips J, Khalil AA, Boehm-Sturm P, Foddis M, Harms C, Fchtemeier M, Dirnagl U

However, TGF-1 has two sides: In addition to being an inducer driving fibrotic and anti-inflammatory responses, its inactivation may also mean exacerbating proinflammatory effects, suggesting that antifibrotic intervention that directly targets TGF- may trigger other unknown risks (145)