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Closely monitor all antidepressant-treated patients for clinical worsening, and for emergence of suicidal thoughts and behaviors[see Warnings and Precautions ( 5.1)]

Patients who already have hair loss, acne, pigmentation, psoriasis, eczema, hidradenitis suppurativa, loose skin concerns or nutritional deficiencies may benefit from a baseline dermatology review before, or early during treatment

and NAM, 7.50 ( 5%)

Univariate/multivariate Cox regression analyses evaluated the association of LVD with a composite outcome (including ischemic stroke recurrence, acute coronary events, and all-cause mortality), and its components separately