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Involvement of miRNA in cancer development was first reported in 2002 with the finding that the miR-15a and miR-16-1 are lost in the B cells of 70% of chronic lymphocytic leukemia patients due to the translocation induced deletion of chromosome 313q14.3 resulting in an increase in anti-apoptotic gene BCL2 product (165)

Growth and molecular responses of tomato to prolonged and short-term heat exposure

Conclusion: Our results suggest that the knockout of miR-21 is sufficient to cause a metabolic syndrome with steatosis and NASH in mice

Moreover, Wnt2 genes found in the autism susceptibility chromosomal locus and several Wnt2 variants are associated with ASD [178,179,180,181,182]