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10.1016/j.jhep.2019.03.014 142 ZhangQ.LuoP.ZhengL.ChenJ.ZhangJ.TangH.et al (2022)

Vicious cycle of iron dyshomeostasis and A/tau An abnormal increase in iron levels in the AD brain is a well-documented phenomenon, especially in the regions most severely affected by neurodegeneration (6)

3.1 Ferroptosis and apoptosis Apoptosis serves as a natural, programmed mechanism in the course of development, effectively eliminating unnecessary cells for an organism to function well