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Description

The objective of this study is to determine the interaction of STAT3 and FXR agonists (IV GW4064 and obeticholic acid [OCA]) in a mouse model of acute cholangiopathy and in vitro

Genes Cells Devoted Mol Cell Mech

GGT activity (d) (n = 6 technical replicates from 3 independent experiments) and cell numbers (e) (n = 3 technical replicates for Cys 2 -free or n = 6 technical replicates for Control or Cys 2 -free + GSH from 3 independent experiments) for cells grown in control (208 M cystine

Phospholipids incorporating PUFAs contain unstable bis-allylic hydrogen atoms, making them highly susceptible to lipid peroxidation, which in turn drives the execution of ferroptosis [15]