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In rodent myocardial infarction models, the hybrid hydrogel demonstrated enhanced M2 macrophage polarization, increased angiogenesis, and improved cardiomyocyte survival, effectively reducing the infarct size, improving wall thickness, and enhancing myocardial contractility

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However, the pooled global prevalence of biopsy-confirmed celiac disease is 0.7% (0.4% in South America, 0.5% in Africa and North America, 0.6% in Asia, and 0.8% in Europe and Oceania)