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Moreover, BH4 can be regenerated by dihydrofolate reductase (DHFR)

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The name came from its observed capacity to lighten fish and frogs, skin color by shielding melanocytes from the darkening effect of the melanocyt-stimulating hormone and gathering melanin granules [134, 135]

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Cell Rep Med (2023) 4(11):101254

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Scavenging nucleic acid debris to combat autoimmunity and infectious disease

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