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These changes shift energy metabolism from glycolysis toward OXPHOS, increase ATP levels and mitochondrial ROS, and activate p53 via ATR-dependent stress signaling

doi: 10.1016/j.redox.2022.102317 7 ChenQZhengWGuanJLiuHDanYZhuLet al

He is the host of the Joint Action podcast and has dedicated his career to improving the lives of people living with osteoarthritis through research, education, and advocacy.CONNECT WITH USNaia Health: one of our trials: @ProfDavidHunterTwitter: @ProfDavidHunter @jointactionorgEmail: [email protected]: www.jointaction.info/podcastIf you enjoyed this episode, don't forget to subscribe to learn more about osteoarthritis from the world's leading experts

Preliminary testing to understand patient-specific gene expression profiles and/or genomic sequencing to reveal genotypic nucleotide variants may assist the precise implementation of such strategies