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In a study, 41 dogs with non-Hodgkins lymphoma were randomly assigned to receive oral pyridoxine or a placebo dailywhile receiving Doxil chemotherapy in a double-blind method

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Recovering the ability of the disc to repair the ECM, re-establishing the proteoglycan content, may have a significant therapeutic effect by increasing disc hydration and thereby improving its biomechanics (Vadal et al., 2015)