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In addition, treatment with enzalutamide (ENZ) and ARV-110, two anti-AR drugs, enhance the sensitivity of AR+ prostate cancer cells to ferroptosis by decreasing the expression of MBOAT2 [91]

Reactive oxygen species (ROS) not only induce DNA hypermethylation but also interfere with histone modifications, leading to impaired oocyte maturation and endometrial dysfunction 10,11

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