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The mitochondrial theory of aging proposes that alterations in mtDNA overload compromise cellular energy metabolism, affecting cellular life span [182]

10.1038/s41591-024-03453-1 [DOI] [PMC free article] [PubMed] [Google Scholar] Nusrat S., Gulick E., Levinthal D., Bielefeldt K

The present review aims to discuss these pathophysiological mechanisms within a framework of physiological notions, online predictive controls, and motor learning

linkers contain two functional groups, including (1) a group for reaction with an antibody (e.g., carboxylic acid), and (2) a carbonyl group (e.g., an aldehyde or a ketone) for reaction with a drug