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FIGURE 2 Within the framework of DM-induced metabolic dysregulation (encompassing lipid/amino acid/carbohydrate metabolism), gut microbiota disruption, and loss of immune homeostasis, the lung emerges as a critical nexus of these systemic interactions

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Further equilibration of roGFP2-iL in redox buffers with varying pH revealed that the fluorescence ratio of roGFP2-iL is pH-insensitive in the physiological range (Figure 3)