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A well-developed meandering river is shown in Figure 13.22

oral less effective due to metabolism

Upon CCCP treatment, Miro interacting with wild-type LRRK2 was degraded with time, while in the LRRK2 G2019S mutant, Miro showed decreased interaction with the mutant as well as resistance to degradation, delaying mitochondrial arrest and clearance in iPSC-derived neurons (Singh et al., 2019)