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Kariya et al., 2018), indicating that the TGF-1-VEGF-A pathway plays a key role in fibrosis-associated peritoneal angiogenesis (Kariya et al., 2018)

Jiang L, Kon N, Li T, et al

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The questions the EPIC trial raised were whether daily oral administration of the drug pimobendan to MVD-affected dogs before they reached heart failure (CHF), (a) was safe and well tolerated, and (b) would prolong the length of time MVD-affected dogs lived before reaching CHF