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Reproduction studies in rats and rabbits resulted in dose-dependent embryo-lethality at omeprazole doses that were approximately 3.4 to 34 times an oral human dose of 40 mg (based on a body surface area for a 60 kg person)

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208 Ultimately, locking in key microbial or genetic markers through low-cost, rapid detection technologies (such as qPCR and microarrays) and conducting interventional clinical trials to verify their value in guiding treatment decisions and improving patient outcomes is the only way for microbiome markers to move from the laboratory to the clinical consultation room