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Alternative routes of administration include oral formulations, transdermal systems (gels and patches), and subcutaneous implants, which allow for more stable serum testosterone concentrations and individualized dosing strategies

Zwiers, A., Fuss, I

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This perspective, supported by the Lancet Commission on Dementia Prevention, Intervention and Care, is grounded in large-scale observational studies linking factors such as low educational attainment, midlife hearing loss, hypertension, obesity, smoking, depression, diabetes, physical inactivity, and social isolation to increased dementia risk (103)