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The ROC curves were generated for each enzyme individually, and a combined analysis using a multivariable logistic regression model was performed to assess the overall predictive value of these markers

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Nonteratogenic Effects Fetal/Neonatal Adverse Reactions Use of opioid analgesics for an extended period of time during pregnancy for medical or nonmedical purposes can result in physical dependence in the neonate and neonatal opioid withdrawal syndrome shortly after birth