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Melasma is a common skin condition in which the body overproduces melanin, creating symmetrical dark brown patches of pigment typically on the face, forehead, upper cheeks, and around the mouth

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Moreover, more recently a family of proteins called peroxiredoxins has been recognized as catalyzing the reduction of H 2 O 2 by GSH and/or other thiols, but with cysteine in its thiolate form, in their active sites rather than selenium-cysteine (Strange et al., 2000)