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doi: 10.1111/ddg.13707 26 Da Cunha CosmeMLLiuzzi SamaterraJFSiso CardenasSAChaviano HernndezJI

The gene comparison between both S. bacillaris strains revealed a significant number of SNPs present in four GSH-related genes, which directly impacted protein primary structure causing amino acid substitutions or deletions, which in turn can potentially impact protein function

Lack of clinical evidence: Although there is encouraging preclinical research indicating the neuroprotective potential of phytochemicals in TBIs, the absence of comprehensive clinical data hinders the ability to substantiate their effectiveness and safety in human patients

Although binding with the regulatory subunits is sufficient to activate Cdk5, its kinase activity can also be regulated by other pathways, such as phosphorylation, S-nitrosylation, sumoylation, and acetylation