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However, lack of biochemical cues and electrical stimulation could hamper satisfactory nerve regeneration

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doi:10.2174/1566523221666211012092855 14

The McCoy 2013 paper extended this work by introducing N- and C-terminal modifications designed to enhance metabolic stability and hydrophobicity, ultimately producing Dihexa (N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) as an orally active, BBB-permeable analog [2]