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Safety Monitoring and Usage Risks General Precautions Professional Administration: This medication is for intramuscular (IM) or intravenous (IV) use only

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These findings align with preclinical data showing that circadian disruption enhances TNBC tumor growth and impairs the time-dependent efficacy of cisplatin therapy, suggesting that both intact circadian signaling and melatonin rhythms are crucial for optimizing chemotherapeutic outcomes 58