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For instance, endometriosis at the late stages requires that mice be evaluated for months to a year, which makes it very hard to keep the animal alive for such a duration

Oxidative Med Cell Longev 2015:986075 [DOI] [PMC free article] [PubMed] [Google Scholar] Choi Y-J, Kang J-S, Park JHY, Lee Y-J, Choi J-S, Kang Y-H (2003) Polyphenolic flavonoids differ in their antiapoptotic efficacy in hydrogen peroxidetreated human vascular endothelial cells

Thus, near-to-invariably, these approaches would study SNPs known or expected to influence cellular or organismal processes linked to CDDP sensitivity, such as CDDP extrusion (e.g., SNPs affecting ABCC2), DNA damage-elicited signal transduction (e.g., SNPs affecting ERCC1), apoptosis (e.g., SNPs affecting caspases) or immune responses (e.g., SNPs affecting cytokines or their receptors)

Mesquita, P